CIC Polyclonal Antibody, 50ul Electrophoresis & Labeling PMID: 15805470)

PMID: 15805470)

Huntington disease-like 1

Alternative splicing and alternative promoter usage results in multiple transcript variants

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta

CIC Polyclonal Antibody, 50ul Electrophoresis & Labeling PMID: 15805470)The protein encoded by this gene is an ortholog of the Drosophila melanogaster capicua gene, and is a member of the high mobility group (HMG) box superfamily of transcriptional repressors. This protein contains a conserved HMG domain that is involved in DNA binding and nuclear localization, and a conserved C terminus. Studies suggest that the N terminal region of this protein interacts with Atxn1 (GeneID: 6310), to form a transcription repressor