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HUS1 Polyclonal Antibody, 20ul Glassware Sets Members of the ribonuclease III

SKU: 22777941601

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HUS1 Polyclonal Antibody, 20ul Glassware Sets Members of the ribonuclease IIIThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C

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Description

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al

This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif

OCRL encodes an inositol polyphosphate 5-phosphatase

effectively detoxifying these molecules

HUS1 Polyclonal Antibody, 20ul Glassware Sets Members of the ribonuclease IIIThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C

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