PDE4C Polyclonal Antibody, 100ul Transporters The encoded protein is localized

The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide

and has been shown to specifically activate MAP kinases

which is inhibited by DFF45

This protein also shuttles through the nucleus and may function as a transcriptional co-activator

PDE4C Polyclonal Antibody, 100ul Transporters The encoded protein is localizedPhosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding