Arrestin-C Polyclonal Antibody, 100ul ADME Humans have six elastase genes

Humans have six elastase genes which encode the structurally similar proteins elastase 1

Engulfment and cell motility protein 1 interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration

Mutations in this gene cause familial hypocalciuric hypercalcemia

is ubiquitously expressed and localized in the cytoplasm

Arrestin-C Polyclonal Antibody, 100ul ADME Humans have six elastase genesThe protein encoded by ARR3 is a non visual arrestin which binds to agonist activated, phosphorylated G protein coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma tubulin to help regulate proper centrosome function.