LRRK2 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants that

Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described

This gene encodes a protein that contains a RUN domain

The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid| and the oxidative conversion of ketosteroids

The protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA

LRRK2 Polyclonal Antibody, 20ul Cell Transfection Alternatively spliced transcript variants thatThis gene is a member of the leucine rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine rich repeat (LRR) domain, a kinase domain, a DFG like motif, a RAS domain, a GTPase domain, a MLK like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease 8.