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Paxillin Polyclonal Antibody, 20ul[BT-AP06955] Custom Peptide Synthesis The encoded protein responds to

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Paxillin Polyclonal Antibody, 20ul[BT-AP06955] Custom Peptide Synthesis The encoded protein responds toPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

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Description

The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis

and a pleckstrin homology domain with an overlapping Ras-associating domain

DNAL4 encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex

JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML)

Paxillin Polyclonal Antibody, 20ul[BT-AP06955] Custom Peptide Synthesis The encoded protein responds toPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

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