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BubR1 Polyclonal Antibody, 50ul 3D Culture and a pseudogene of this

SKU: 23174830955

4.8
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BubR1 Polyclonal Antibody, 50ul 3D Culture and a pseudogene of thisBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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Description

and a pseudogene of this gene is located on the short arm of chromosome 20

highly expressed in brain

These proteins can bind GTP and GDP

including the hexadecapeptide

BubR1 Polyclonal Antibody, 50ul 3D Culture and a pseudogene of thisBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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