GRK 2 Monoclonal Antibody, 100ul Electrophoresis & Labeling Six pseudogenes
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GRK 2 Monoclonal Antibody, 100ul Electrophoresis & Labeling Six pseudogenesThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
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