PARK2 Polyclonal Antibody, 20ul Antibody Humanization Dok-5 protein undergoes tyrosine phosphorylation

Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1

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The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase

Stimulates cancer-associated fibroblast (CAF) proliferation by a rapid genomic response through the EGFR/ERK transduction pathway

PARK2 Polyclonal Antibody, 20ul Antibody Humanization Dok-5 protein undergoes tyrosine phosphorylationThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this