FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 100ul Microplate Mixer Transcripts for this gene undergo

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

20 min) processes

Alternative splicing results in multiple transcript variants| some of which are derived from alternative promoter usage

MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit

FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 100ul Microplate Mixer Transcripts for this gene undergodisease: A chromosomal aberration involving FOXO4 is found in acute leukemias. Translocation t(X; 11)(q13; q23) with MLL HRX. The result is a rogue activator protein. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin response elements (IREs) and can activate transcription of IGFBP1. Down regulates expression of HIF1A and suppresses hypoxia induced transcriptional activation of HIF1A modulated genes.