Beclin-1 Polyclonal Antibody, 20ul Cell Dissociation Tumor necrosis factor receptor superfamily

Tumor necrosis factor receptor superfamily member 1B encoded by TNFRSF1B is a member of the TNF-receptor superfamily

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins

This gene is classified as a pseudogene because a splice donor in the 3' UTR has changed compared to other family members| rendering the transcript a candidate for nonsense-mediated mRNA decay (NMD)

Allelic variants of this gene are associated with microcephaly

Beclin-1 Polyclonal Antibody, 20ul Cell Dissociation Tumor necrosis factor receptor superfamilyThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.