Paxillin Polyclonal Antibody, 50ul[BT-AP06955] Sampling Tubes Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been found

and a tyrosine phosphorylation site

The protein is also a coreceptor for human immunodeficiency viruses (HIV)

A minor proportion is also found at nuclear pore complexes and around the pericentriolar matrix of mitotic centromeres

Paxillin Polyclonal Antibody, 50ul[BT-AP06955] Sampling Tubes Alternatively spliced transcript variants encodingPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.