TP53INP2 Polyclonal Antibody, 100ul[BT-AP09143] Variant Libraries |disease:A chromosomal aberration involving NFKB2

|disease:A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line

Aberrant expression of this gene is associated with cancer progression in multiple tissues

The activity of the protein is negatively regulated by its SH3 domain

it includes an F5/8 type C domain

TP53INP2 Polyclonal Antibody, 100ul[BT-AP09143] Variant Libraries |disease:A chromosomal aberration involving NFKB2The protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.