Rat Glutaredoxin-1, GLRX ELISA Kit, 96T Cellular Function Assays Stimulates both innate and acquired

Stimulates both innate and acquired immune responses through the activation of specific target genes and can act as a transcriptional activator and repressor regulating target genes by binding to an interferon-stimulated response element (ISRE) in their promoters (PubMed: 15226432

PubMed: 21529378

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains

The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED)

Rat Glutaredoxin-1, GLRX ELISA Kit, 96T Cellular Function Assays Stimulates both innate and acquiredHas a glutathione disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.