SIG10 Polyclonal Antibody, 50ul Bottles The product of this gene

The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils

but do not bind mutant p53

This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members

The encoded protein activates a Gq signal transduction pathway which mobilizes calcium

SIG10 Polyclonal Antibody, 50ul Bottles The product of this geneSIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B cell expressed SIGLEC6 (MIM 604405).