Eme1 Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene are

Mutations in this gene are associated with type 1 elliptocytosis (EL1)

Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis

The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor

Saethre-Chotzen syndrome

Eme1 Polyclonal Antibody, 20ul Cell Function Analysis Mutations in this gene areEME1 encodes essential meiotic structure specific endonuclease 1 that complexes with methyl methanesulfonate sensitive UV sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3' flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in