CD55 Polyclonal Antibody, 50ul[BT-AP01838] Glassware Alternative splicing of NUB1 results

Alternative splicing of NUB1 results in multiple transcript variants

This gene is widely expressed in human tissues and has increased expression in actively dividing cells

Mutations in this gene cause aminoacylase-1 deficiency| a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids

Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546

CD55 Polyclonal Antibody, 50ul[BT-AP01838] Glassware Alternative splicing of NUB1 resultsTight junctions represent one mode of cell to cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The