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IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis This protease has been shown

SKU: 25102685451

4.1
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IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis This protease has been shownIRS2 (insulin receptor substrate 2) encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor associated

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Description

This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor

this gene has been found to be hypermethylated in multiple cancer types

resulting in nuclear localization and activation

Alternative splicing results in multiple transcript variants encoding the same protein

IRS2 Polyclonal Antibody, 50ul ssDNA Synthesis This protease has been shownIRS2 (insulin receptor substrate 2) encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor associated

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