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PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 50ul[BT-AP11860] Liquid Handling &Storage breast stomach and pancreas

SKU: 25430391151

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PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 50ul[BT-AP11860] Liquid Handling &Storage breast stomach and pancreasPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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breast stomach and pancreas

The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor

A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1)| and binds to alpha- and beta-dystrobrevins| which are components of the dystrophin-associated protein complex (DPC)

A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta

PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 50ul[BT-AP11860] Liquid Handling &Storage breast stomach and pancreasPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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