MLXPL Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis VAV2 transcripts were found in

VAV2 transcripts were found in most tissues

Mutations in APP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy)

The encoded intracellular glycoprotein is localized at the endoplasmic reticulum

There are two isoforms of this protein

MLXPL Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis VAV2 transcripts were found inThis gene encodes a basic helix loop helix leucine zipper transcription factor of the Myc Max Mad superfamily. This protein forms a heterodimeric complex and binds and activates in a glucose dependent manner carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams Beuren syndrome a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11. 23.