PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification USP53 (Ubiquitin Specific Peptidase 53)

USP53 (Ubiquitin Specific Peptidase 53) is a Protein Coding gene

The encoded protein plays a role in many cellular processes including cell cycle progression

This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway

It is the vertebrate homologue of the yeast protein Mex67p

PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification USP53 (Ubiquitin Specific Peptidase 53)The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in