LXR Alpha Polyclonal Antibody, 50ul Funnels so this may be a

so this may be a tumor suppressor gene

Along with a similar protein| HMGN1| the encoded protein may help maintain an open chromatin configuration around transcribable genes

Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype

The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin

LXR Alpha Polyclonal Antibody, 50ul Funnels so this may be aOxysterols receptor LXR alpha encoded by NR1H3 belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes