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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This protein has been found

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Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This protein has been foundLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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Description

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

This gene encodes a protein containing an alpha/beta hydrolase fold| which is a catalytic domain found in a very wide range of enzymes

The genomic region is also rich in Alu repetitive sequences

It is highly conserved in vertebrates and most abundantly expressed in the brain

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use This protein has been foundLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

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