Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0955] Gene Synthesis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding the same isoform have been identified

but our experiment always detected a 60-70kDa protein by western blot

a component of the 40S subunit

have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain

Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0955] Gene Synthesis Alternatively spliced transcript variants encodingThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation