NCoA-5 Polyclonal Antibody, 50ul Recombinant Protein Expression Several alternatively spliced transcript variants

Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic

The encoded protein is involved in natural killer cell development and function

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA

NCoA-5 Polyclonal Antibody, 50ul Recombinant Protein Expression Several alternatively spliced transcript variantsNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this