PCNA Monoclonal Antibody(12D10), 20ul Shakers RAB3 GTPase activating non-catalytic protein

RAB3 GTPase activating non-catalytic protein subunit 2 encoded by RAB3GAP2 belongs to the RAB3 protein family

Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1)

which has been shown to be responsible for binding ATP and may help promote cell survival

Alternative splicing results in at least two different transcript variants

PCNA Monoclonal Antibody(12D10), 20ul Shakers RAB3 GTPase activating non-catalytic proteinThe protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have