Hrs Polyclonal Antibody, 100ul[BT-AP04216] Buffer Solutions Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms exist

q12) translocation with the Ewing sarcoma gene on chromosome 22

The encoded protein is a sodium-independent cationic amino acid transporter

It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene

Hrs Polyclonal Antibody, 100ul[BT-AP04216] Buffer Solutions Alternatively spliced transcript variants encodingThe protein encoded by HGS (hepatocyte growth factor regulated tyrosine kinase substrate) regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.