AFF4 Polyclonal Antibody, 20ul Plates & Dishes The protein encoded by the

The protein encoded by the c-mpl gene| CD110| is a 635 amino acid transmembrane domain| with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs

and tumorigenesis

which is involved in initiation of transcription of genes by RNA polymerase II

which are related to growth

AFF4 Polyclonal Antibody, 20ul Plates & Dishes The protein encoded by theThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).