NRG4 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis The encoded protein interacts with

The encoded protein interacts with many other proteins| including the platelet integrin alpha-IIb-beta-3| DNA-dependent protein kinase| presenilin-2| focal adhesion kinase| p21 activated kinase| and protein kinase D

The encoded protein itself is found in a complex of proteins

This gene encodes a 25-kD microfibril-associated glycoprotein which is a component of microfibrils of the extracellular matrix

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

NRG4 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis The encoded protein interacts withThe neuregulins, including NRG4, activate type 1 growth factor receptors (see EGFR; MIM 131550) to initiating cell to cell signaling through tyrosine phosphorylation (Harari et al., 1999