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GPC1 Polyclonal Antibody, 50ul Immuno Plates The synphilin-1 interacts with alpha-synuclein

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GPC1 Polyclonal Antibody, 50ul Immuno Plates The synphilin-1 interacts with alpha-synucleinCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

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Description

The synphilin-1 interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration

The encoded protein contains six extracellular cadherin domains| a transmembrane domain| and a cytoplasmic tail differing from those of the classical cadherins

Mutations in KRT18 have been linked to cryptogenic cirrhosis

Genes in this family encode components of the circadian rhythms of locomotor activity

GPC1 Polyclonal Antibody, 50ul Immuno Plates The synphilin-1 interacts with alpha-synucleinCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

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