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IRAK-1 Polyclonal Antibody, 20ul[BT-AP04618] Cell Transfection The encoded protein (complement C6)

SKU: 28168236970

4.2
SEK111.00 SEK143.00

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IRAK-1 Polyclonal Antibody, 20ul[BT-AP04618] Cell Transfection The encoded protein (complement C6)IRAK1 encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein (complement C6) is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis

Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma

Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported

HK3 encodes hexokinase 3

IRAK-1 Polyclonal Antibody, 20ul[BT-AP04618] Cell Transfection The encoded protein (complement C6)IRAK1 encodes the interleukin 1 receptor associated kinase 1, one of two putative serine threonine kinases that become associated with the interleukin 1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1 induced upregulation of the transcription factor NF kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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