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CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries This gene is expressed in

SKU: 28169162804

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PLN141.00 PLN188.00

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CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries This gene is expressed inCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants

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Description

This gene is expressed in both normal and tumor cells

The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS

Alpha chains of type IV collagen have a non-collagenous domain (NC1) at their C-terminus| frequent interruptions of the G-X-Y repeats in the long central triple-helical domain (which may cause flexibility in the triple helix)| and a short N-terminal triple-helical 7S domain

This gene encodes a male meiotic metaphase chromosome-associated acidic protein

CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries This gene is expressed inCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants

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