Vasohibin Polyclonal Antibody, 20ul Centrifugal Filter is a lysosomal cysteine proteinase

is a lysosomal cysteine proteinase that may play an important role in corneal physiology

Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations

the protein encoded by this gene may play a role in vascular development and remodeling

Several alternatively spliced transcript variants encoding different isoforms of this gene have been described

Vasohibin Polyclonal Antibody, 20ul Centrifugal Filter is a lysosomal cysteine proteinaseAngiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage