XIAP Polyclonal Antibody, 20ul CellSafe™ The SH2 domain interacts with

The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin

Also recognizes and binds tRNAs

Catalyzes the rapid transport across the plasma membrane of many monocarboxylates

The antigen is being used as a target for immunotherapy treatment of human carcinomas

XIAP Polyclonal Antibody, 20ul CellSafe™ The SH2 domain interacts withXIAP encodes E3 ubiquitin protein ligase XIAP that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti apoptotic function. This protein functions through binding to tumor necrosis factor receptor associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1 beta