PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The DUX gene family

The DUX gene family

Isoform 4 is expressed in lung and pancreas (at protein level)

Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway

They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development

PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The DUX gene familyThe protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic