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MKP-2 Polyclonal Antibody, 100ul Mammalian Expression A mutation in this gene

SKU: 2885216565

4.4
PLN141.00 PLN191.00

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MKP-2 Polyclonal Antibody, 100ul Mammalian Expression A mutation in this geneThe dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different

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Description

A mutation in this gene was found in an individual with Leigh syndrome

with a suggested role in the process of spermatogenesis

Detected on cytoplasmic membranes in undifferentiated tumors

which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762)

MKP-2 Polyclonal Antibody, 100ul Mammalian Expression A mutation in this geneThe dual specificity phosphatase 4 encoded by DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different

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