NIF3L Rabbit Polyclonal Antibody, 20ul sgRNA Oligos Mice lacking this gene show

Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes

The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat

This gene is classified as a pseudogene because a splice donor in the 3' UTR has changed compared to other family members| rendering the transcript a candidate for nonsense-mediated mRNA decay (NMD)

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD)| which may facilitate formation of heterotrimeric or multi-protein complexes

NIF3L Rabbit Polyclonal Antibody, 20ul sgRNA Oligos Mice lacking this gene show