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Rb Polyclonal Antibody, 50ul[BT-AP07687] Cytokines BAI1 contains at least one

SKU: 29310407390

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Rb Polyclonal Antibody, 50ul[BT-AP07687] Cytokines BAI1 contains at least oneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

BAI1 contains at least one 'functional' p53-binding site within an intron

This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored| cell membrane protein

They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins

whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors

Rb Polyclonal Antibody, 50ul[BT-AP07687] Cytokines BAI1 contains at least oneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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