GPR45 Polyclonal Antibody, 100ul Cell Culture Dishes Mutations that result in the

Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia

is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation

FASTKD1 is a gene on chromosome 2q31 that encodes an enzyme belonging to the FAST kinase domain-containing protein family that contains a RAP domain

2002 [PubMed 12191433])

GPR45 Polyclonal Antibody, 100ul Cell Culture Dishes Mutations that result in theThis intronless gene encodes a member of the G protein coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.