SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome a disease characterized by recurrent

a disease characterized by recurrent bacterial infections

The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex

the encoded protein contains 2-43 copies of kringle-type domains

An important paralog of this gene is GPR21

SPTC2 Rabbit Polyclonal Antibody, 100ul Lysosome a disease characterized by recurrentThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.