Histone H3 Monoclonal Antibody(Mix), 20ul Culture Tubes The TERF1 interacting nuclear factor

The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin

Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer

Diseases associated with GP1BA include von willebrand disease

Upon activation

Histone H3 Monoclonal Antibody(Mix), 20ul Culture Tubes The TERF1 interacting nuclear factorHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin