CYH2 Rabbit Polyclonal Antibody, 100ul Cell Dissociation This gene (NME1) was identified

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells

The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase

This gene is expressed in kidney

This gene is located at a chromosomal region commonly deleted in Williams syndrome

CYH2 Rabbit Polyclonal Antibody, 100ul Cell Dissociation This gene (NME1) was identifiedThe protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N terminal coiled coil motif a central Sec7 domain and a C terminal pleckstrin homology (PH) domain. The coiled coil motif is involved in homodimerization the Sec7 domain contains guanine nucleotide exchange protein (GEP) activity and the PH domain interacts with phospholipids and is responsible for