CD110 Polyclonal Antibody, 100ul[BT-AP01341] Monoclonal Antibodies Sestrins are induced by the

Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways

The expression of NTF4 is ubiquitous and less influenced by environmental signals

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

CD110 Polyclonal Antibody, 100ul[BT-AP01341] Monoclonal Antibodies Sestrins are induced by theIn 1990 an oncogene, v mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c mpl, was cloned. Sequence data revealed that c mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti sense oligodeoxynucleotides of c mpl inhibited megakaryocyte colony