UVRAG Polyclonal Antibody, 50ul Organelle Studies It is also thought to

It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion

This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH

Up-regulated upon mitogenic stimulation

Deficiency of this enzyme is generally asymptomatic

UVRAG Polyclonal Antibody, 50ul Organelle Studies It is also thought toThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.