Cbl Polyclonal Antibody, 20ul[BT-AP01264] Vacuum Filter This gene is found to

This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL)

which sequester the cytosol and organelles for degradation by lysosomes

permeable filter membrane cap ensures sterility and facilitates gas exchange

Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia

Cbl Polyclonal Antibody, 20ul[BT-AP01264] Vacuum Filter This gene is found toCBL is a proto oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein (Cbl proto oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine phosphorylated