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Granzyme M Polyclonal Antibody, 20ul Antibody Humanization Contributes to thymic atrophy by

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Granzyme M Polyclonal Antibody, 20ul Antibody Humanization Contributes to thymic atrophy byHuman natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have

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Description

Contributes to thymic atrophy by inducing apoptosis

can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis

A non-transcribed pseudogene of this locus is found on chromosome 19

and pericentriolar regions of cells

Granzyme M Polyclonal Antibody, 20ul Antibody Humanization Contributes to thymic atrophy byHuman natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have

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