Rat Insulin-like 3, INSL3 ELISA Kit, 96T Serum ABCB5 belongs to the ATP-binding

ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins

Is a key player in the control of plasma membrane curvature

PubMed: 9162022)

Inhibits the PI3K-AKT-mTOR pathway possibly by directly interacting with the posphatidylinositol 3-kinase regulatory subunit p85 (PIK3R1/PIK3R2) and disrupting the association between PIK3R1/PIK3R2 and the catalytic subunit p110 (PIK3CA/PIK3CB/PIK3CD) and reducing PIK3R1/PIK3R2 activation

Rat Insulin-like 3, INSL3 ELISA Kit, 96T Serum ABCB5 belongs to the ATP-bindingSeems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity).