CNOT6 Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The two chains A and

The two chains A and B are held together by a single disulfide bond

This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain

A pseudogene of this gene has been defined on chromosome 5

a type I keratin

CNOT6 Rabbit Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The two chains A andThis gene encodes the catalytic component of the CCR4 NOT core transcriptional regulation complex. The encoded protein has a 3' 5' RNase activity and prefers polyadenylated substrates. The CCR4 NOT complex plays a role in many cellular processes including miRNA mediated repression mRNA degradation and transcriptional regulation.