DOCK7 Polyclonal Antibody, 100ul Syringe Filter contributed by the association of

contributed by the association of RUVBL1 and RUVBL2 with EP400

and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G)

BBS proteins may also be involved in intracellular trafficking via microtubule-related transport

It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta

DOCK7 Polyclonal Antibody, 100ul Syringe Filter contributed by the association ofThe protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene.