SNX1 Polyclonal Antibody, 50ul Purification G proteins are trimeric (alpha-beta-gamma)

G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors

Several transcript variants encoding different isoforms have been found for ARNTL

Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome

The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells

SNX1 Polyclonal Antibody, 50ul Purification G proteins are trimeric (alpha-beta-gamma)SNX1 encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Sorting nexin 1 regulates the cell surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease activated receptor 1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members.